Robert De Niro

John Wesley “Jack” Walsh

Charles Grodin

Jonathan Mardukas aka “The Duke”

Yaphet Kotto

Alonzo Mosely, Special Agent, F.B.I.

John Ashton

Marvin Dorfler, Headhunter

Dennis Farina

Jimmy Serrano, Chicago mobster

Joe Pantoliano

Eddie Moscone, Bail Bonder

Richard Foronjy

Tony Darvo, Serrano's henchman

Robert Miranda

Joey, Serrano's henchman

Jack Kehoe

Jerry Geisler, Tony's secretary

Wendy Phillips

Gail, Jack's ex-wife

Philip Baker Hall

Sidney, Chicago mobster

Tom Irwin

F.B.I. Agent Perry

Jimmie Ray Weeks

F.B.I. Agent Tuttle

Danielle DuClos

Denise Walsh, Jack's daughter

Tom McCleister

Red Wood, Bar Tender

Mary Gillis

Bus Ticket Clerk

John Toles-Bey

Monroe Bouchet

Thomas J. Hageboeck

Sergeant Gooch

Stanley White

Stanley

Scott McAfee

Boy on Plane

Linda Cerasuolo

Car Rental Clerk

Lois Smith

Mrs. Nelson, Mardukas's Friend

Fran Brill

Dana Mardukas, Jonathan's Wife

Michael Hawkins

FBI Surveillance Agent #1

John Hammil

FBI Surveillance Agent #2

Lou Felder

Airline Pilot

Cameron Milzer

Stewardess #1

Sonia M. Roberts

Stewardess #2

Sam Sanders

Train Porter

Frank Pesce

Carmine

Paul Joseph McKenna

Ohio Policeman

Matt Jennings

Jason

Rosemarie Murphy

Coffee Shop Waitress

Jack N. Young

Amarillo Desk Sergeant

Robert Coleman

Native American

William Robbins

Native American

Wilfred Netsosie

Native American

Sherman L. Robbins

Native American

Dale Beard Jr.

Native American

Thomas Nez

Native American

Richard Gonzalez

Bar Cashier

Bill Fritz

Bar Customer

Pete Jensen

Flagstaff Police Captain

Andy Charnoki

Flagstaff Sheriff

Tracey Walter

Diner Counter Man

Robert Vento

Serrano Bodyguard

Joe "Tippy" Zeoli

Serrano Bodyguard

James Portese

Serrano Bodyguard

Armando Muniz

Serrano Bodyguard

Dan York

Las Vegas FBI Agent #1

Rowdy Burdick

Las Vegas FBI Agent #2

Varnoy Lee

Airport Porter

Bob Maroff

L.A. Taxi Driver

Martin Brest

Airline Ticket Clerk (uncredited)

Lisa Burnett

Undercover Cop (uncredited)

George D. Miklos

Airport Manager (uncredited)

Robert Minkoff

Man (uncredited)

Marguerite Nocera

Ticket Clerk (uncredited)

Terry Ray

Deplaning Passenger (uncredited)

Jock L. Schloss

Man (uncredited)

D. Danny Warhol

Station Commuter (uncredited)