Gary Cooper

Captain Christopher Holden

Paulette Goddard

Abby

Howard Da Silva

Garth

Boris Karloff

Guyasuta, Chief of the Senecas

Cecil Kellaway

Jeremy Love

Ward Bond

John Fraser

Katherine DeMille

Hannah

Henry Wilcoxon

Captain Steele

C. Aubrey Smith

Lord Chief Justice

Victor Varconi

Captain Simeon Ecuyer

Virginia Grey

Diana

Porter Hall

Leach

Mike Mazurki

Bone

Richard Gaines

Colonel George Washington

Virginia Campbell

Mrs. John Fraser

Gavin Muir

Lieut. Fergus McKenzie

Alan Napier

Sir William Johnson

Ninetta Sunderland

Mrs. Pruitt

Marc Lawrence

Medicine Man Sioto

Jane Nigh

Evelyn

Raymond Hatton

Venango Scout

John Mylong

Colonel Henry Bouquet

George Kirby

London Astronomer Charles Mason

Leonard Carey

London Astronomer Jeremiah Dixon

Frank Wilcox

Richard Henry Lee

Davison Clark

Mr. Carroll of Virginia

Griff Barnett

Brother Andrews of Pennsylvania

Lloyd Bridges

Lieut. Hutchins

Oliver Thorndike

Lieut. Baillie

Rus Conklin

Mamaultee

Iron Eyes Cody

Red Corn

Julia Faye

Widow Swivens

Paul E. Burns

Dan McCoy

Mary Field

Maggie

Diane Wadelow

Lancashire Lass

Clarence Muse

Jason

Cecil B. DeMille

Self - Narrator (voice) (uncredited)

Dorothy Adams

Woman at Fort Pitt (uncredited)

James Flavin

Villager (uncredited)

Francis Ford

Frontiersman on Fort Pitt Roof (uncredited)

Byron Foulger

Townsman (uncredited)

Beulah Archuletta

Seneca Woman (uncredited)