Micah Abbey

Donatello (voice)

Shamon Brown Jr.

Michelangelo (voice)

Nicolas Cantu

Leonardo (voice)

Brady Noon

Raphael (voice)

Ayo Edebiri

April O'Neil (voice)

Maya Rudolph

Cynthia Utrom (voice)

John Cena

Rocksteady (voice)

Seth Rogen

Bebop (voice)

Rose Byrne

Leatherhead (voice)

Natasia Demetriou

Wingnut (voice)

Giancarlo Esposito

Baxter Stockman (voice)

Jackie Chan

Splinter (voice)

Ice Cube

Superfly (voice)

Paul Rudd

Mondo Gecko (voice)

Post Malone

Ray Fillet (voice)

Hannibal Buress

Genghis Frog (voice)

Jimmy Donaldson

Times Square Guy (voice)

Derek Wilson

Spider (voice)

Lukas Williams

Curious Goon (voice)

Michael Badalucco

Bad Bernie (voice)

Dempsey Pappion

Bald Bronson (voice)

John Capodice

Cab Driver (voice)

Andia Winslow

TV Anchor (voice)

Raechel Wong

News Anchor (voice)

David Faustino

Normal Nate (voice)

Danny Mastrogiorgio

Toupee Tom / Police Officer (voice)

Noel Gibson

Responding Police Officer / Military Advisor (voice)

Myra Owyang

Short Sharon (voice)

Kevin Eastman

Good Human (voice)

Alex Hirsch

Bossy Goon / Scumbug (voice)

Mike Rianda

Paycheck Goon / Chop Shop Boss / Ratatouille Guard (voice)

Bobby Wagner

Man Who Thought a Giant Rat was a Big Cat but was a Rat (voice)

Greg Levitan

Gecko Goon (voice)

Illya Quinteros

Helpful Construction Worker (voice)

Natalie Canizares

Sign My Baby Mom (voice)

Kyler Spears

Apologetic Goon (voice)

Jeff Rowe

Man Who Loves Being Young and Free to Go Places (voice)

Matthew Broderick

Ferris Bueller (archive footage) (uncredited)

Aaron Hardy

Police Officer (voice)