Andy Samberg

Nyles

Cristin Milioti

Sarah

J.K. Simmons

Roy

Peter Gallagher

Howard

Meredith Hagner

Misty

Camila Mendes

Tala

Tyler Hoechlin

Abe

Chris Pang

Trevor

Jacqueline Obradors

Pia

June Squibb

Nana Schlieffen

Tongayi Chirisa

Jerry

Dale Dickey

Darla

Conner O'Malley

Randy

Jena Friedman

Daisy the Bartender

Brian Duffy

Spuds

Martin Kildare

Ted the Bartender

Lilli Birdsell

Jamie

Ryan Sturtz

Cop

Clifford V. Johnson

Professor

Calki Garcia

DJ Nice Height

Michelle Johnston

Nosy Neighbor

Isla Sellers

Roy's Daughter

Matt Smith

Out of Town Dad

Rebecca Smith

Out of Town Mom

Jake Smith

Out of Town Older Son

Noah Smith

Out of Town Younger Son

Rocky Bonifield

Wedding Guest (uncredited)

Erin Flannery

Wedding Guest (uncredited)

David Hutchison

Biker (uncredited)

Mark Kubr

Biker (uncredited)

David Philip Reed

Truck Driver (uncredited)