Helen Hayes

Lucille Jefferson

Van Heflin

Stedman

Dean Jagger

Dan Jefferson

Robert Walker

John Jefferson

Minor Watson

Dr. Carver

Frank McHugh

Father O'Dowd

Richard Jaeckel

Chuck Jefferson

James Young

Ben Jefferson

Jimmie Dundee

Taxi Driver (uncredited)

Douglas Evans

Government Employee (uncredited)

Nancy Hale

Nurse (uncredited)

Sam Harris

Professor at Graduation Ceremony (uncredited)

Todd Karns

Bedford (uncredited)

Leo McCarey

John Jefferson (voice) (uncredited)

Lee Miller

Policeman at Shooting Scene (uncredited)

David Newell

FBI Agent (uncredited)

Vera Stokes

Secretary (uncredited)

Fred Sweeney

Cleaner (uncredited)

Margaret Wells

Nurse (uncredited)