Jim Belushi

Homer Lanza

Whoopi Goldberg

Eddie Cervi

John Waters

Robber #1

Robert Glaudini

Robber #2

James Thiel

Twin #1

Jeff Thiel

Twin #2 (as Jeffrey Thiel)

Andy Jarrell

Trucker

Anne Ramsey

Edna

Jim Mapp

Harmonica Player

Michelle Milantoni

Fat Woman in Pizza Joint

Mickey Jones

Man at Pizza Joint

Annie O'Donnell

Wife at Pizza Joint

Katherine Barrese

Waitress

Tad Horino

Mickey

Karen Black

Belle

Jack Goode Jr.

Tawdry Man

Ernestine McClendon

Esther

Pruitt Taylor Vince

Cashier

Wayne Grace

Preacher

Smitty Smith

Man Shoveling Snow

Lee Armstrong

Husband at Fruit Stand

Jan Bina

Wife at Fruit Stand

Harry Caesar

Street Person

Al Noble

Street Crazy #1

Louis B. Scott Sr.

Street Crazy #2

Sebastian Massa

Bartender

Tommy Lister Jr.

Man in Bar with Gun

Mae Mercer

Ellen

Pat Ast

Maggie Sinclair

Nick LaTour

Bar Customer

Beah Richards

Linda Cervi

Boris Aplon

Driver in Fancy Car

Angelyne

Blonde

Tony Epper

Gas Station Attendant

Vincent Schiavelli

Priest

Jimmie F. Skaggs

Jesus #1

Nancy Parsons

Maid

Tracey Walter

Tommy Dearly

Fritz Feld

Mortician

Barbara Pilavin

Mrs. Lanza

Angelo Bertolini

Mr. Lanza

Sasha Barrese

4-Year-Old Girl

Don Hanmer

Cashier #2

Ed DeFusco

Bobby French

Yelena Koreneva

Mark Winn

Homeless man (uncredited)