Alec Baldwin

Theodore Templeton (voice)

James Marsden

Tim Templeton (voice)

Amy Sedaris

Tina Templeton (voice)

Ariana Greenblatt

Tabitha Templeton (voice)

Jeff Goldblum

Dr. Armstrong (voice)

Eva Longoria

Carol Templeton (voice)

James McGrath

Wizzie (voice)

Jimmy Kimmel

Ted Templeton (voice)

Lisa Kudrow

Janice Templeton (voice)

Raphael Alejandro

Nathan / Lead Baby Ninja (voice)

Serenity Reign Brown

Meghan (voice)

David Soren

Jimbo (voice)

Nicholas Gist

The Triplets (voice)

James Ryan

Story Bear (Connie) (voice)

David P. Smith

Movie Patron (voice)

Nova Reed

Little Bo Peep Baby (voice)

Molly K. Gray

Creepy Girl (voice)

Ashlyn Lundahl

'No' Girl (voice)

Dave Needham

Glue Baby (voice)

Tom McGrath

Dr. Tiffany Hamilton (voice)

Reyn Doi

Box Kid (voice)

Collin Erker

Time Out Kid (voice)

Walt Dohrn

Baby Bouncer (voice)

April Lawrence

Acorn Center Computer (voice)

Miles Bakshi

Young Tim Voice-Over (voice)

Kristin Lowe

Pageant Mom 1 (voice)

Marjorie Cohn

Pageant Mom 2 (voice)

Connor Albrecht

Dreidel Kid (voice)