Jon Voight

Alfred Kroeber

Graham Greene

Ishi

David Ogden Stiers

Dr. Saxton Pope

Jack Blessing

Tom Waterman

Anne Archer

Henriette Kroeber

Daniel Benzali

Mr. Whitney

Christianne Hauber

Miss Edna Block

Charles Martinet

Assistant Museum Director

Carl D. Parker

Sheriff Weber

Angela Paton

Mrs. Gustafson

Benne Alder

Mrs. Whatley

Marie Bain

Nurse

Loryn Barlese

Ishi's Young Sister

Gilbert Bear

Ishi's Father

Lance Brady

Reporter #4

Roy Conrad

Reporter #2

Kevin Goetz

Medical Student

Neva Hutchinson

Mrs. Berney

John Ickes

Museum Director (as John Z. Ickes)

Trudy Kinerson

Ishi's Sister

Beverly LaBeau

Ishi's Mother

Stephen Lofaro

Doctor

George Maguire

Mr. Whatley

Edward Markmann

Photographer

Wanda McCaddon

Woman with Hat

Sean David McClelland

Reporter #3

C.W. Morgan

Rudy

James O'Connell

Wester Union Operator

John Olson

Museum Goer

Stephen Pocock

Bob

Christopher Pray

Reporter #1 (as Chris Pray)

Victor Preston

Ishi's Uncle

Nick Scoggin

Alcott

Toby Stump

Young Ishi

Brian VanDerWilt

Student

Anthony Snow

Museum Patron (uncredited)

Kerry van der Griend

Bicycle Rider (uncredited)