Lacey Chabert

Eliza Thornberry (voice)

Tom Kane

Darwin (voice)

Cree Summer

Phaedra (voice)

Tim Curry

Nigel Thornberry (voice)

Lynn Redgrave

Cordelia Thornberry (voice)

Danielle Harris

Debbie Thornberry (voice)

Flea

Donnie Thornberry (voice)

Crystal Scales

Cheetah Cubs (voice)

Kimberly Brooks

Tally (Cheetah Cub) (voice)

Alfre Woodard

Akela (Cheetah Mother) (voice)

Brock Peters

Jomo (voice)

Melissa Greenspan

Sarah Wellington (voice)

Alexandra Boyd

Victoria (voice)

Moira Quirk

Jane (voice)

Jodi Carlisle

Marianne Thornberry (voice)

Mae Whitman

Schoolgirl (voice)

Marisa Tomei

Bree Blackburn (voice)

Rupert Everett

Sloan Blackburn (voice)

Earl Boen

Gorilla (voice)

Jack Angel

Poachers (voice)

Bob Bergen

Poachers (voice)

Bill Farmer

Poachers (voice)

Kevin Michael Richardson

Shaman Mnyambo (voice)