Lacey Chabert

Eliza Thornberry (voice)

Tom Kane

Darwin (voice)

Cree Summer

Phaedra (Elephant) (voice)

Tim Curry

Nigel Thornberry / Col. Radcliff Thornberry (voice)

Lynn Redgrave

Cordelia Thornberry (voice)

Jodi Carlisle

Marianne Thornberry (voice)

Danielle Harris

Debbie Thornberry (voice)

Flea

Donnie Thornberry (voice)

Crystal Scales

Cheetah Cubs (voice)

Kimberly Brooks

Tally (Cheetah Cub) (voice)

Alfre Woodard

Akela (Cheetah Mother) (voice)

Brock Peters

Jomo (voice)

Melissa Greenspan

Sarah Wellington (voice)

Alexandra Boyd

Victoria (voice)

Moira Quirk

Jane (voice)

Tara Strong

Schoolgirl (voice)

Hynden Walch

Schoolgirl (voice)

Mae Whitman

Schoolgirl (voice)

Roger L. Jackson

Reggie (Squirrel) / Thunder (voice)

John Kassir

Squirrel (voice)

Charles Shaughnessy

Squirrel (voice)

Brenda Blethyn

Mrs. Fairgood (voice)

Kevin Michael Richardson

Shaman Mnyambo (voice)

Billy Brown

Rhino (voice)

Marisa Tomei

Bree Blackburn (voice)

Rupert Everett

Sloan Blackburn (voice)

Jeff Coopwood

Tim (Park Ranger) (voice)

Didier M. Ngole

Ranger / BaAka Villager (voice)

Tony Okungbowa

Ranger (voice)

James Brown Orleans

Zebu (voice)

Michael Chinyamurindi

Cart Owner (voice)

Earl Boen

Gorilla (voice)

Obba Babatundé

Boko (voice)

Malonga Casquelourd

BaKA Leader (voice)

Alu Amina

BaKA Villager (voice)

Nsaka Kaninda

BaAka Villager (voice)

B. Dido Tshimanga

BaAka Villager (voice)

Camille Ntoto

BaAka Villager (voice)

Colette Elimo

BaAka Villager (voice)

Lunkeba Tezo

BaAka Villager (voice)

Jeanne Klimi

BaAka Villager (voice)

Inousca Kayombo

BaAka Villager (voice)

Mata Mokwala

BaAka Villager (voice)

Keith Szarabajka

Poacher (voice)