Hugh Laurie

Sam Bell

Joely Richardson

Lucy Bell

Adrian Lester

George

Matthew Macfadyen

Nigel

Yasmin Bannerman

Melinda

Joanna Lumley

Shiela

Rowan Atkinson

Mr. James

Emma Thompson

Druscilla

James Purefoy

Carl Phipps

Tom Hollander

Ewan Proclaimer

Rachael Stirling

Joanna

Dave Thompson

Dave the Comedian / Mrs. Furblob

Stephen Simms

Trevor

John Brenner

Kit

Jaz Wilson

Baby Cuthbert

Richard Leaf

Justin Cocker

Paul Ready

Student Doctor

John Lightbody

Hospital Administrator

Mina Anwar

Yasmin

John Fortune

Acupuncturist

Kelly Reilly

Nimnh

Dawn French

Charlene

Serena Evans

Dr. Cooper

Lisa Palfrey

Jan

Judi Shekoni

Ewan's Posse

Lidija Zovkić

Petra

Paul Tripp

Mr. Furblob