Colin Farrell

Captain Smith

Q'orianka Kilcher

Pocahontas

Christopher Plummer

Captain Newport

Christian Bale

John Rolfe

August Schellenberg

Powhatan

Wes Studi

Opechancanough

David Thewlis

Wingfield

Yorick van Wageningen

Captain Argall

Raoul Max Trujillo

Tomocomo

Michael Greyeyes

Rupwew

Kalani Queypo

Parahunt

Ben Mendelsohn

Ben

Noah Taylor

Selway

Brían F. O'Byrne

Lewes

Ben Chaplin

Robinson

Jamie Harris

Emery

Janine Duvitski

Mary

Eddie Marsan

Eddie

Joe Inscoe

Ackley

Jake Curran

James

John Savage

Savage

Thomas Clair

Patawomeck

Alex Rice

Patowomeck's Wife

Irene Bedard

Pocahontas' Mother

Ford Flannagan

Winthrop

Bev Appleton

Small

Billy Merasty

Kiskiak

Jonathan Pryce

King James

Alexandra W.B. Malick

Queen Anne

Jasper Britton

Laureate

Myrton Running Wolf

Tockwhogh

E. Danny Murphy

Bosun

Jonathan Gonitel

Thomas - 4 Yrs

Brian Merrick

Assailant

Chris Nelson

Chris

Colin Cox

Cox

Will Wallace

William Sentry

Steven Dawn

Goldsmith

Rulan Tangen

Two Moons

Jesse Borrego

Pepaschicher

Todd Wallace

Sailor

Kirk Acevedo

Sentry

Nive Nielsen

Inuit Woman

Tayla Kean

Cabin Boy 1

Thomas Steven McDonagh

Cabin Boy 2

James McDonagh

Cabin Boy 3

Gary Sundown

Messenger

Michael Goodwin

Helmsman

Sam Stevenson

Young Lady

Maria Pastel

Rosalind

Raynor Scheine

Raynor

Jeremy Radin

Jeremy

Matthew Yeung

Shaman

Gregory Labenz

Sentry 2

Miraida Rios

(voice actor)